The suspension was filtered on 70μm mesh filters to retain only single cells. Cells were plated in macrophage growth medium [DMEM/F12 (Corning), 10% FBS (Sigma), 1% Penicillin/Streptomycin (Corning), ...

The three-signal paradigm tries to capture how the innate immune system instructs adaptive immune responses in three well-defined actions: (1) presentation of antigenic peptides in the context of MHC ...

We present a case of M4 acute myelomonocytic leukemia (AMML) without cytogenetic abnormalities, in which spontaneous remission (SR) occurred after a severe coronavirus infection, along with multiple ...

From the Centers of Inflammation, Translational, and Clinical Lung Research (Y. Shao, Y. Sun, Y.L., F.S., C.D., C.J., K.X., X.J., X.Y.), Temple University, Lewis Katz ...

At the end of my previous column,1 I briefly discussed the fact that the NIST CSF 2.0 calls for “a hierarchy of executives, managers and practitioners not stated in the previous version.” This is not ...

iQue Qbeads ® is considered a family of reagents allowing the capture of particular proteins on separate bead types. This permits multiplexed quantitation of adhesion molecules, cytokines ...

These trials will help inform whether blunting the inflammatory signaling provided by the GM-CSF axis in COVID-19 is beneficial. Data supporting the role of hyperinflammation in sepsis-related acute ...

PBMCs were isolated from the blood of healthy donors by centrifugation on Ficoll-Hypaque Plus (GE Biotech) following the manufacturer’s protocol, and the CD14-enriched fraction was collected after ...

Here, we show that deletion of the main transcription factor involved in heat shock gene regulation, heat shock factor 1 (HSF1), affects M-CSF-driven differentiation of mouse bone marrow cells.