Benign liver tumors (BLT) are extremely frequent, varied, and mostly asymptomatic. Each cellular component of the liver (e.g., hepatocyte, biliary, endothelial, or other mesenchymal cells ...

Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1–HER3 signaling. Nature Cancer , 2025; DOI: 10.1038/s43018-024-00882-2 Cite This Page : ...

Molecular Zip Code Draws Killer T Cells Straight to Brain Tumors Dec. 5, 2024 — Scientists have developed a 'molecular GPS' to guide immune cells into the brain and kill tumors without harming ...

Breast cancer metastases are initiated by cancer cells that detach from the primary tumor and migrate to other organs via the bloodstream. These circulating cancer cells (CTCs) are extremely rare ...

These cancers should be treated with surgery, radiation, targeted therapy, and chemotherapy. Germ Cell Tumors Germ cell tumors form from egg cells and grow in the ovary. They can be benign or ...

The findings are published in Science Advances in an article titled, “Engineered extracellular vesicles with DR5 agonistic scFvs simultaneously target tumor and immunosuppressive stromal cells.” ...

This is a useful report of a spatially-extended model to study the complex interactions between immune cells, fibroblasts, and cancer cells, providing insights into how fibroblast activation can ...

The adoptive transfer of TCR-T cells specific to neoantigens preferentially exhibits potent cytotoxicity to tumor cells and has shown promising efficacy in various preclinical human cancers. In this ...

"The study could guide future research on cell origins, gene mutations, the construction of animal models, drug screening, and tumor growth mechanisms using reverse translational research," he said.