Quince Therapeutics, Inc. (Nasdaq: QNCX), a late-stage biotechnology company dedicated to unlocking the power of a patient’s ...

ataxia-telangiectasia-like disorder, Nijmegen breakage syndrome and Alzheimer's disease) exhibit defects in genes involved in repairing double-strand breaks. The current overall picture indicates ...

In this paper the authors have identified two new participants in the damage-response pathway, using cells from patients with ataxia-telangiectasia [AT], a disease characterized by hypersensitivity to ...

The event brought together 300 researchers, clinicians, industry leaders, and entrepreneurs to highlight their work.

The ATM gene (mutated in the disease ataxia telangiectasia) activates the p53 tumor suppressor protein in response to DNA damage, explaining the higher incidence of cancer in AT patients.

The Rhode Island Neuroscience Symposium gathered 300 researchers, clinicians, industry leaders and entrepreneurs yesterday to ...

Optimization of Potent and Selective Ataxia Telangiectasia-Mutated Inhibitors Suitable for a Proof-of-Concept Study in Huntington’s Disease Models. Journal of Medicinal Chemistry, vol.

Short for ataxia telangiectasia and Rad3-related kinase ... Another woman with advanced ovarian cancer whose disease had come back after treatment with a drug blocking PARP, another key DNA ...