重磅!1月21日,刊登在国际权威期刊《eLife》上的一项突破性研究,彻底颠覆了我们对阿尔茨海默病的传统认知!科学家们发现,这个困扰人类数十年的神秘疾病,其真正的元凶可能并非我们一直以来认定的β淀粉样蛋白堆积,而是大脑中一个关键的"蛋白质加工厂"的"停工"!
Prolonged rapid eye movement (REM) latency may be a potential marker for Alzheimer disease and Alzheimer disease and related dementias (AD/ADRD).
虽然人类研究显示,tau 和淀粉样相关的神经回路功能障碍在 AD 患者的记忆障碍中存在分离效应和相互作用,但 Aβ 和 tau 如何相互作用导致认知和神经精神症状仍不清楚。此外,Aβ 和 tau 导致突触功能障碍以及情感和记忆神经回路易损性的神经病理相互作用机制也尚未明确。
Alzheimer's disease (AD) is a chronic neurodegenerative disorder that is characterized by memory and physical impairment in aged individuals. microRNAs (miRNAs) are small, single-stranded noncoding ...
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For years, scientists have focused on amyloid beta buildup as the main culprit in Alzheimer’s disease, but a new study suggests the real problem might lie in a stalled protein-cutting process in the ...
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Research indicates longer REM latency is associated with higher Alzheimer's biomarkers, pointing to its potential as an early ...
People with diabetes have a higher risk of developing Alzheimer's disease (AD) raising a possible link between the cells that ...
The study indicated delayed REM sleep is a novel marker or risk factor for AD/ADRD pathogenesis. Throughout the study, Prolonged REML (rapid eye movement latency) was associated with higher amyloid ...
Prolonged rapid eye movement (REM) sleep latency was linked with Alzheimer's disease biomarkers, cross-sectional data showed.