The ERBB receptors are a group of receptor tyrosine kinases (RTKs) involved in key cellular functions including cell growth and survival. What are the activation mechanisms particular to ERBBs?

Inhibikase Therapeutics announced disappointing results from a Phase 2 trial for its Parkinson’s disease drug, risvodetinib, ...

Investigators conducted a retrospective review that spanned 10 years with the goals of describing the clinical ...

ERBB receptors are regulated by their own intrinsic properties as well as by external associated proteins. What is regulation, where does it occur on the receptor, and how do scientists study it?

Sorafenib is an oral multikinase inhibitor that inhibits tumor growth and proliferation by interfering with several receptor tyrosine kinases involved in the pathogenesis and perpetuation of ...

and receptor-like kinases (RLK). RLK is structurally similar to receptor-tyrosine kinases (RTKs) in animals, while RLP is ...