Chimeric antigen receptor-T (CAR-T) cell therapy, initially successful in hematologic malignancies, presents a promising avenue for treating solid tumors, including CRC. This review explores the ...
Giving an additional receptor to T cells that might already be targeting cancer naturally might also “over-activate” those cells, leading to quicker exhaustion of immune cells. Or trogocytosis ...
Get Instant Summarized Text (Gist) The inflammasome, a group of immune proteins, can prevent blood stem cells from becoming cancerous by removing specific receptors and inhibiting cancer gene activity ...