Researchers found that bioengineered CAR-T cells when mixed with other immune cells can "donate" proteins, suggesting ...

In vitro, MATEs promote potent activation of murine and human T cells, induce their proliferation and trigger T cell-mediated bystander toxicity. MATEs can be expressed by an oncolytic adenovirus and ...

Talimogene laherparepvec (T-VEC) demonstrates efficacy in cutaneous BCC, enhancing resectability and altering immune cell ...

Researchers at Cellectis leveraged gene editing to create a CAR T cell that acts in an IF/THEN system. Traditional methods to develop CAR T cells that use the patient’s cells introduce challenges ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

The Phase III trial builds on findings from prior findings that indicated Anktiva can restore T-cell function and improve ...

Scientists have progressed from merely provoking an anti-cancer immune response to designing it ...

Dr. Won Jin Ho presented a talk as part of the Immunology Neighborhood Seminar on “Overcoming the tumor immune ...

The three-signal model provides an empirical framework for innate instruction of adaptive immunity, but mainly discusses STAT-dependent cytokines in T cell activation and differentiation, while the ...