Activation of the NOTCH1 receptor ... degradation of the protein. 15 Lymphoma cells from a pleural effusion in a pediatric patient with T-cell lymphoblastic disease at relapse were obtained ...

Also, mutation of the miR-21 binding site on exon 4 of GAS5 gene to generate a GAS5 mutant abolished its ability to regulate miR-21 expression as well as T cell activation and apoptosis markers ...

Cells were treated with varying concentrations of DHA, and CD4 + and CD8 + T cell activation markers (CD38 and HLA-DR) were measured via flow cytometry. This study provides insights into the ...

A personalized neoantigen cancer vaccine generated strong immune responses in renal cell carcinoma patients, leading to ...

Different CAF‐targeting strategies are being explored for stroma normalization including elimination of CAFs using CAR-T cells against CAF surface markers like fibroblast activation protein (FAP).

Different HAART combinations may have a different effect on T cell activation markers. We investigated the expression of activation markers in a group of naïve HIV-positive patients starting different ...

Immune cells called regulatory T cells have long been known for their role in countering inflammation. In the setting of ...

The authors examined human plaque samples and identified a small proportion of plaque T cells as T RMs (4.6 %) using clustering based on single-cell RNA sequencing data and previously established ...

A recent study carried out by a research team from the Paul-Ehrlich-Institut investigated the immunomodulating properties of ...

8 Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA Correspondence to Dr Marina Pasca di Magliano, PhD, Department of Surgery and Department of Cell and Developmental ...

E) UMAP of subsetted and reclustered Tetramer+ CD8 T cells showing three different clusters. F) RNA expression in Tetramer+ CD8 T cells of curated activation markers. G) UMAP of Tetramer+ CD8 T cells ...