Inhibitory synaptic transmission is a crucial aspect of how neurons communicate and maintain balance in the brain. GABA (gamma-aminobutyric acid) is the primary neurotransmitter responsible for ...

Right: Distribution of coefficients of variation of interspike intervals for E and I neurons. (G) Distribution (across neurons) of time-averaged synaptic inputs to E (left) and I neurons (right). In E ...

Synaptic plasticity is the biological process by which specific patterns of synaptic activity result in changes in synaptic strength and is thought to contribute to learning and memory. Both pre ...

Weill Cornell Medicine investigators have identified in a preclinical model a specific brain circuit whose inhibition appears ...

Meanwhile, blocking EPS markedly rescued synaptic density, and motor function deteriorated by chemogenetic inhibition. In addition, C1q-blocking antibody prevented phosphatidylserine engulfment by ...

Drugs targeting amyloid plaques have failed to show efficacy in clinical trials. A new approach is needed to tackle AD ...

Neuropilin2 controls migration of inhibitory neurons as well as the formation and maintenance of synaptic connections in excitatory neurons—two crucial components of brain activity. A study led ...

Researchers found that random brain fluctuations actually strengthen memory by stabilizing neural activity over time. The ...

Emerging evidence suggests that lycopene—a natural plant extract—may have antidepressant properties. New research in Food Science & Nutrition reveals the mechanisms behind its antidepressant effects.

Institute of Flexible Electronics (IFE, Future Technologies), Xiang’an Campus, Xiamen University, Xiang’an South Road, Xiamen 361102, Fujian, China State Key Laboratory of Physical Chemistry of Solid ...