Objectives Human urate transporter 1 (URAT1) is a member of the organic anion transporter family (SLC22A12) that primarily regulates the renal tubular reabsorption of uric acid. This case–control ...

Empagliflozin use can reduce the risk of calcium and uric acid kidney stones in patients without diabetes, new data show. In the double-blind, single-center, phase 2 SWEETSTONE trial ...

the target SU was achieved by 60.5% of underexcretors compared with 39.0% of patients of the unclassified excretion type group at the 12th week (P = 0.002) without significant clinically important or ...

Elevated uric acid in children with severe malaria is associated with increased risks of death and long-term cognitive ...

PK and sUA lowering effects in patients with renal impairment and normal renal function were also compared ... Urine samples were collected for assessment of uric acid excretion. Laboratory safety ...

Amino acid metabolism is closely related to the kidney. On the one hand, the absorption, release, metabolism, and excretion of amino acids by the kidney can effectively regulate the level of amino ...

Scientist develop new equation for detecting hyperfiltration that incorporates age but not body surface area. Read more!

Kidney stones, those tiny, rock-hard deposits that can bring even the toughest individuals to their knees, are on the rise globally. If you think you’re immune, think again. Recent studies ...

Toxicity of colchicine is also increased by renal or hepatic failure ... Uricase degrades relatively insoluble uric acid to the more soluble compound allantoin. Urate reabsorption by urate ...

Although chicken is a lean meat with high nutritional value, if you have gout (also called gouty arthritis), you need to be careful about: The cuts you choose How much you eat How you prepare it Gout ...

Renal hypoplasia, defined as abnormally small kidneys with normal morphology and reduced nephron number, is a common cause of pediatric renal failure and adult-onset disease. Genetic studies ...