Figure 4: Regulation of IgL gene recombination ... by receptor signalling in developing B cells. The identification of the PI3K–PKB pathway as part of autonomous receptor signalling, which ...

Pathogen exposure stimulates static cells, which activate the TLR signaling pathway (green). This leads to an initial outbreak of the proinflammatory cytokine, which are then greatly amplified in the ...

Accumulating evidence suggested that Nrf2 antioxidant pathway might be one of key regulatory targets for the health-promoting effects of NPs. However, the information concerning regulation of NPs on ...

UMD researchers have discovered key mechanisms in gene regulation that could improve the design of RNA-based medicines.

Understanding how cells transform into specialized types during human development is a central challenge in biology. This complex process, known as cell differentiation, holds the key to understanding ...

The hypoxic response pathway Cells respond to low oxygen levels through stabilization of the HIF1/2α transcription factors. This is a complex system with multiple levels of regulation ...

(figure 4G). In Cell Fate 1, the enrichment of pathways like the Wnt pathway and glandular development was commonly found elevated in adenoma cells. In Cell Fate 2, enriched signals were predominantly ...

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...

Cell cycle re-entry of senescent breast cancer cells after CDK4/6 inhibition (CDK4/6i) constitutes a major source of disease ...

Mitochondria, often seen as cellular powerhouses, play a surprising role in immune regulation. Researchers found that ...

This study provides a valuable new resource to investigate the molecular basis of the particular features characterizing the pipefish embryo. The authors found both unique and shared gene expression ...