Result and discussion: We show that human dendritic cells (DCs) and LCs have a previously unknown primary cilium-like structure. The primary cilium was assembled during DC proliferation in response to ...

By reexamining 3D images used to map the connections between brain cells, researchers are uncovering new information about a small, elusive, and often overlooked cellular appendage.

Distal appendages are nine-fold symmetric blade-like structures attached to the distal end of the mother centriole. These structures are critical for formation of the primary cilium, by regulating at ...

Cilia are derived from BBs, and the centrioles are the primary structure of the BBs. As a result, numerous dysfunctions of the centriole will interfere with the normal proliferation of ependymal cilia ...

However, the centriole, the structure from which the cilium grows ... Ott et al, Permanent deconstruction of intracellular primary cilia in differentiating granule cell neurons, Journal of ...

This article was accepted for publication via eLife's original publishing model. eLife publishes the authors' accepted manuscript as a PDF only version before the full Version of Record is ready for ...