Objective: The purpose of the present study was to demonstrate clinical equivalence between the application of collagenase ointment at 24- and 48-hour intervals in the healing of pressure ulcers.

Ulcers were staged according to the American Pressure Ulcer Advisory Panel ... entered into an active run-in period with collagenase ointment (Iruxol® Mono, Laboratorios Knoll, SA, Madrid ...