The results highlight an important physiological function of PGAM in the differentiation and suppressive activity of Treg cells by regulating serine synthesis. This role is proposed to intersect with ...

PIN1 then changes that protein's shape. Phosphorylation of proteins at serine residues next to prolines is known to be a major signaling mechanism controlling cell proliferation and malignant ...

PIN1 then changes that protein's shape. Phosphorylation of proteins at serine residues next to prolines is known to be a major signaling mechanism controlling cell proliferation and malignant ...

It involves uncoupling of mitochondrial oxidative phosphorylation which alters the intercellular junction and increases intestinal permeability with consequent intestinal damage. Metronidazole ...

In this review, I summarize recent findings on the molecular mechanisms of Reelin activity. I also discuss possible strategies to enhance Reelin’s function. A complete understanding of Reelin function ...

Another focus is to understand the interplay between protein phosphorylation and protein ubiquitylation in regulating the innate ... is a remarkable E3 ligase that attaches ubiquitin to serine and ...

1 Sino-British Research Centre for Molecular Oncology, Department of Pathology, Zhengzhou University, China 2 Centre for Molecular Oncology & Imaging, Institute of Cancer, Barts and The London School ...