Researchers have discovered how a particular protein affects the growth and spread of colon cancer in humans. The study not ...

in part through the dephosphorylation of Cdk regulators. Therefore, much remains to be learned about the phosphatases that govern the phosphorylation states of Cdk substrates during late mitosis ...

The current human tissue-based study provides convincing evidence correlating hippocampal expressions of RNA guanine-rich G-quadruplexes with aging and with Alzheimer's Disease presence and severity.

p27 proteolysis is initiated by several different mechanisms. Tyrosine (Tyr) phosphorylation of p27 by Abl and Src family kinases reduces p27–CDK2 inhibition and transforms p27 from inhibitor to ...

1 Eye Center of the 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China 2 Zhejiang Provincial Key Lab of Ophthalmology, Hangzhou, Zhejiang, China Purpose: To ...

Therefore, the notion that increased Ub phosphorylation leads to protein aggregation in mouse hippocampal neurons is not yet convincingly supported. (2) The specificity of PINK1 and p-Ub antibodies ...