Conclusions Cardiovascular effects are identifiable in childhood even in mild forms of OI. Aortic dilation was the predominant finding, while valvular abnormalities were infrequent. Patients with more ...

USA 4 Departments of Pathology and Medicine, University of Washington, Seattle, WA, USA Correspondence to: Dr N H Robin, Center for Human Genetics, Lakeside 1500, Cleveland, OH 44106-6506, USA; ...