Scientists from the German Cancer Research Center (DKFZ) and ShanghaiTech University have developed an innovative method for ...

We successfully established a sigmoid colon cancer organoid using this tissue and investigated drug screening in the patient. HE staining, immunohistochemistry, and DNA sequencing were utilized to ...

Organoid technology, as a cutting-edge technology ... such as incomplete microenvironmental simulations the lack of the simulation of the intricate nature of multi-organ interactions in vivo, and the ...

研究人员指出，LXR作为一种调节因子，在促进受损肠道愈合、再生的同时，可以抑制结直肠癌肿瘤的生长，对于维持肠道稳态具有重要作用，这种相互调节机制为肠道生物学和理解疾病机制提供了新见解。未来，通过进一步探索LXR激活在组织再生和肿瘤发生中差异效应的潜在机制，有望作为治疗靶点成为免疫抑制剂的有效替代方案，为IBD 患者带来新的治愈希望。

The pioneering respiratory organoid culture system allows scientists ... rhinovirus C and elucidation of virus-host interaction, Nature Communications (2024). DOI: 10.1038/s41467-024-55076-2 ...

Children's Mercy Kansas City has achieved a significant advancement toward the treatment of rare genetic diseases through the use of personalized antisense oligonucleotides (ASOs). This innovative ...

Nature Research Intelligence gives you a greater focus on real-world impact, enabling you to find the most effective strategies and collaborations to deliver maximum benefit from your research ...

Jan. 23, 2025 — Rising carbon dioxide levels affect more than just the climate; they also affect the chemistry of the oceans. When saltwater absorbs carbon dioxide, it becomes acidic, which ...