and determine cell-autonomy of gene action. The cellular and molecular mechanisms that ensure the elaborate connection and function of the nervous system can then be dissected with single neuron ...

and another gene linked to neuronal cell death to express more. "Our findings indicate these genes may be markers to detect and monitor PFAS-induced neurotoxicity in the future," says lead co ...

Of these, five neuronal subtypes accounted for 99% of TL neurons, with LS neurons almost exclusively populating the remaining two subtypes. We identify and classify neurons based on novel ...

This study provides a valuable new resource to investigate the molecular basis of the particular features characterizing the pipefish embryo. The authors found both unique and shared gene expression ...

Drugs targeting amyloid plaques have failed to show efficacy in clinical trials. A new approach is needed to tackle AD ...

Through the years, advancements in genetic markers, immunostaining, optical and electro-optical methods, electrophysiology, and computational tools have been made to identify neuronal types, explain ...

As reported January 14 in Neuron, scientists led by first author Emmy Li, now at Stanford University, California, and Martin Kampmann of the University of California, San Francisco, used this new ...

a protein crucial for neuron survival. At the same time, it up-regulated thioredoxin-interacting protein, which is linked to cell death. “Each of these 11 genes exhibited consistent regulation across ...

Loss of neuronal RBM20 has only modest impact on alternative splice isoforms but results ... For Ribo-TRAP pull-down experiments, all the samples presenting enrichment of the wrong marker genes were ...