Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in various tumor cells in vitro, but its physiological role in tumor surveillance remains unknown. Here ...
In the present work the opposite mechanism is investigated; that is, whether and how inflammatory cells can activate intracellular proteases. Design Using mice either deficient for the CD18-α subunit ...
SBL03 was formulated as an ophthalmic gel for non-invasive topical delivery. Its unique ability to infiltrate eye tissues effectively and protect ret ...
Each cytokine acts through its own receptor on target cells, and these receptors include members of the immunoglobulin (Ig) superfamily and tumour necrosis factor (TNF). Cell-type-specific SARS ...
Nanjing Reju Therapeutics Inc. has described tumor necrosis factor receptor type 1-associated DEATH domain protein (TRADD) inhibitors reported to be useful for the treatment of inflammatory-related ...