[11] Beta blockers, including carvedilol, also decrease heart rate, myocardial contractility, and myocardial oxygen demand. Carvedilol also decreases systemic vascular resistance via its a ...

This fundamental work extends our understanding of the role of TGFβ2 as a modulator of mechanosensing in the eye and identifies the TRPV4 ion channel as a common regulator of Trabecular Meshwork (TM) ...

Consequently, when regional contractility deteriorates because of ischaemia, the amplitude of shortening during ejection time decreases, and early systolic lengthening (ESL) and PSS are observed in ...

This review examines the cardiovascular risks associated with cannabis, revealing its potential to cause severe heart health ...

Specifically, before revascularization, 804 of 2,093 myocardial segments analyzed (38%) had abnormal contractility, and 694 segments (33%) had some areas of hyperenhancement. Among all 804 ...

EHM allografts restore heart muscle safely, offering a breakthrough in heart failure treatment with no arrhythmia risk.

It appears that in cardiac muscle an inotropic shift of V max of the contractile element cannot be distinguished from a shift due to change in fiber length, thus invalidating it as an index of ...

The term dilated cardiomyopathy (DCM) refers to a spectrum of heterogeneous myocardial disorders that are characterized by ventricular dilation and depressed myocardial performance in the absence of ...

These molecules may regulate blood pressure, vascular tone, and myocardial contractility, implicating their potential implications relevant to examining diseases such as hypertension, heart failure, ...

Background: The efficacy of dexmedetomidine (DEX) in treating sepsis-induced myocardial injury (SIMI) remains unclear. In this study, we explored the relationship between DEX use and clinical outcomes ...