Although numerous genes can be associated with monogenic diabetes, it is heterozygous mutations in six of them that are responsible for the majority of MODY cases. Glucokinase (GCK)-MODY is caused by ...

Introduction: Monogenic diabetes (MD) accounts for 3%–6% of all cases of diabetes ... The aim of this study is to identify genetic loci and causative mutations in Tunisian suspected MD patients using ...

Monogenic Diabetes Monogenic diabetes is a rare type caused by a change in a single gene ... The first symptom to appear is diabetes mellitus, usually diagnosed around age six, and optic atrophy ...

Monogenic diabetes is a rare type caused by a change ... and optic atrophy (progressive vision loss) around age 11. Mutations in the WFS1 gene cause this condition; the WFS1 gene gives ...

Both neonatal diabetes and MODY are monogenic, and both tend to be incorrectly diagnosed ... who have a 50% chance of inheriting a gene mutation. Unfortunately, insurance often denies coverage for ...

An emerging field of genetics promises to let parents choose the “healthiest” baby.

More specifically, the traditional understanding of type 2 diabetes genetics has focused on a dichotomy between monogenic and polygenic forms. However, emerging evidence suggests a continuum that ...

Competing Interests: The authors declared no competing interests. Monogenic hypertension is caused by single gene mutations and accounts for a spectrum of familial forms of elevated blood pressure ...

8 Since a mutation can be found in ∼80% of patients with definite FH, the majority of this group have a monogenic cause. By contrast, a mutation can only be detected in 25%–30% of patients with ...