Extranodal non-Hodgkin lymphoma (NHL) makes up over one-third of NHL cases, yet remains understudied and in need of deeper ...

In patients with RCC, exceptional response to immunotherapy may be related to clonal neoantigen-driven cytotoxic T-cell ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

Innate lymphoid cells (ILCs) are immune cells that belong to the lymphoid lineage but do not express antigen-specific receptors. These cells have important functions in innate immune responses to ...

A brain tumor is a mass of abnormal cells that grow in the brain. Brain tumors can be benign (non-cancerous) or malignant (cancerous) and can start anywhere in the brain. Malignant tumors grow rapidly ...

What Is Lymphoma? Lymphoma is a cancer of the lymphoid tissue, which includes both cells and organs. It affects the same organs of the lymphatic system (thymus, bone marrow, lymph nodes, spleen). But ...

Tertiary lymphoid structures (TLSs) (1, 2) are organized clusters of immune cells that develop ... contributing significantly to the complex interplay of immune cells and tumor cells within the TME.

A pioneering new treatment promises to tackle a wider range of cancers, with fewer side-effects than conventional radiotherapy. It also takes less than a second. In a series of vast underground ...

When a child develops a brain tumor, early diagnosis is essential. Alan Cohen, M.D., director of pediatric neurosurgery at Johns Hopkins Children’s Center, shares the most common signs and symptoms ...

TLSs pop up in many tissues, including most tumors, where they have been associated ... unusual type of immune cell called group 2 innate lymphoid cells (ILC2s) might have anti-cancer effects ...

A research team at Memorial Sloan Kettering Cancer Center (MSK) has made new insights into how the body forms immune cell clusters called tertiary lymphoid structures (TLSs) in response to foreign ...

This stimulated TLSs to form in pancreatic tumors. The team went on to show ... IL-33-activated ILC2s induce tertiary lymphoid structures in pancreatic cancer, Nature (2025).