Paul Vaillant-Couturier, F-94807 Villejuif Cedex, France; laurent.orsi{at}inserm.fr Objectives Investigating the role of occupational exposure to solvents in the occurrence of lymphoid neoplasms (LNs) ...

In this review, we aim to provide a comprehensive summary of the existing classifications for TLS maturity and therapeutic strategies capable of inducing its formation in tumors. The formation of TLS ...

Tertiary lymphoid structures (TLSs) (1, 2) are organized clusters of immune cells that develop ... contributing significantly to the complex interplay of immune cells and tumor cells within the TME.

"One of the things that struck us when we looked at these tumors was that patients who were responding to immunotherapy had tertiary lymphoid structures," he says. Like lymph nodes, the structures ...

Extranodal non-Hodgkin lymphoma (NHL) makes up over one-third of NHL cases, yet remains understudied and in need of deeper ...

TLSs pop up in many tissues, including most tumors, where they have been associated ... unusual type of immune cell called group 2 innate lymphoid cells (ILC2s) might have anti-cancer effects ...

A research team at Memorial Sloan Kettering Cancer Center (MSK) has made new insights into how the body forms immune cell clusters called tertiary lymphoid structures (TLSs) in response to foreign ...

This stimulated TLSs to form in pancreatic tumors. The team went on to show ... IL-33-activated ILC2s induce tertiary lymphoid structures in pancreatic cancer, Nature (2025).

Innate lymphoid cells (ILCs) are immune cells that belong to the lymphoid lineage but do not express antigen-specific receptors. These cells have important functions in innate immune responses to ...

A research team at Memorial Sloan Kettering Cancer Center (MSK) has made new insights into how the body forms immune cell clusters called tertiary lymphoid ... including tumors, to bolster the ...

Vinod Balachandran identified the molecular pathway involved in the formation of tertiary lymphoid structures ... including tumors, to bolster the local immune response. Understanding the ...