The locus coeruleus is emerging as a major new area of research interest, with many important functions such as regulating ...

The locus coeruleus–norepinephrine system is thought to be involved in the clinical effects of vagus nerve stimulation. This system is known to prevent seizure development and induce long-term plastic ...

The locus coeruleus is emerging as a major new area of research interest, with many important functions such as regulating our attention and sleep. Anyone with insomnia knows the impatience and ...

What has puzzled researchers and philosophers for many centuries is the ‘why’ of sleep, along with the ‘how’. We human animals know from experience that we need to sleep, ...

At the end of the experiment, the rats under anesthesia were infused via the left ventricle with 4% paraformaldehyde in 0.01 M phosphate buffer solution (pH 7.4), brain segments containing region of ...

This important study shows that the activity of hypothalamic hypocretin/orexin neurons (HONs) correlates with body movement over multiple behaviors. Sophisticated techniques and analyses showcase this ...

很多人都乐意在咖啡浓郁诱人的香味中，开启自己清醒的一天。我们似乎能切实感受到咖啡在身体内起效的那一刻，雾蒙蒙的大脑和眼睛中的世界似乎瞬间被擦干净了，整个世界突然变得清晰明亮起来。 清醒与睡眠 ...

The US government has provided almost $24 million in funding to Locus Biosciences to support a mid-stage trial of LBP-EC01, a CRISPR-engineered bacteriophage therapy in development for resistant ...

Like VNS, the mechanism of action is not well understood, but is thought to involve deactivation of the nucleus of the solitary tract and the locus coeruleus. TNS differs from VNS in several important ...

This work shows that concussion, even without symptoms, causes neuron death, with ATF3-expressing layer V cortical neurons more vulnerable than those in layer II/III. The authors investigate ...