The density corresponding to Neu5Ac and sodium ions are in purple. The substrate binding sites of apo and Neu5Ac bound FnSiaQM are shown with key residues labeled. The density (blue mesh) around these ...

Significant advances have been made over the last 10 years in our understanding of both the clinical and molecular features of STGD1 ... Further robust longitudinal prospective natural history studies ...

Department of Chemistry, University of Wisconsin−Madison, Madison, Wisconsin 53706, United States ...

However, mechanistic studies to support the conclusion that mitochondrial function is increased in the tumours remain incomplete and would benefit from experiments that would directly interrogate ...

This study offers insights into the regulation of cell adhesion and the design of drug delivery antibodies by showing that an antibody which traps P-cadherin in a distinct extracellular structure ...