Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana 46202, United States Department of Pharmacology and Toxicology, Indiana University School of Medicine, ...

Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including ...

CRASH-2 trial collaborators, Lancet, 376:23-32, 2010. 3. Focus on focal adhesions » The architecture of focal adhesions—structures that mediate signaling and adhesion to the extracellular matrix—is ...

TOR signalling and integrin signalling. Protein kinase R-like endoplasmic reticulum kinase-phosphorylated adenylosuccinate lyase (ADSL) binds to Beclin1 upon lipid deprivation. ADSL-produced ...

Studies by Jeffrey Klomp et al. 6 and Jennifer Klomp et al. 7 refine our understanding of the signaling effects of oncogenic KRAS. The studies suggest that mutant KRAS signals predominantly ...

Moreover, the study identified integrin beta 2 (ITGB2) as a potential target for endometriosis, which is also the target of Lifitegrast, an FDA-approved small molecule integrin antagonist ...

Generate consensus 3D cells segmentations by combining 2D cell segmentations from any combination of xy, xz, yz views, compatible with outputs of any 2D segmentation method.

Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced its 2025 priorities and upcoming ...

Your body temperature can fluctuate at any time. When you experience a much higher body temperature increase, a fever may be the result. If that happens, there are different ways to break a fever ...

"Some people may leave our platforms for virtue signaling, but I think the vast majority and many new users will find that these changes make the products better." Zuckerberg was replying to a ...

Zuck/Threads “Some people may leave our platforms for virtue signaling, but I think the vast majority and many new users will find that these changes make the products better,” Zuckerberg wrote.