While whisker plucking prevents the maturation of feedforward inhibition onto excitatory neurons in the barrel cortex (Chittajallu and Isaac, 2010), the mechanisms engaged in driving GABAergic synapse ...

The characteristics of perforated synapses are consistent with this scenario. That CaMKII is also an essential trigger for this structural change is supported by the finding that inhibition of ...

Conclusions: Donepezil induced inhibition of cortical AChE enzyme activity is modest in patients with mild AD. The degree of cortical enzyme inhibition correlates with changes in executive and ...

Synapse formation is a critical step in the assembly of neuronal circuits. Both secreted and membrane-associated proteins contribute to the formation and maturation of synapses. The process of ...

We show here that expression of a mutant catalytic subunit of human telomerase results in complete inhibition of telomerase activity, reduction in telomere length and death of tumor cells.

Amritanshi Pandey topped the 7th batch of BSc nursing from College of Nursing, Command Hospital, Lucknow, and was commissioned as a lieutenant in military nursing service. Recognized for ...

Scientists have progressed from merely provoking an anti-cancer immune response to designing it ...

Jan. 15, 2025 — Tourette syndrome is currently diagnosed about three times more frequently in males than in females. A new study finds that female individuals are less likely to be diagnosed ...

This can include: being rude saying things that aren’t appropriate (for example, that someone is overweight) talking to strangers undressing in public apparent loss of sexual inhibition (for example, ...

Feb. 6, 2025 — A research team has discovered that the two key pathological hallmarks of Alzheimer's -- tau protein and beta-amyloid -- affect brain circuits in ...