Fig. 1. Workflow of the HMCGDA model. (a) Construct gene-phenotype-disease heterogeneous graph and metapath subgraph. (b) Generate enhanced view, extract features and aggregate to get node embeddings.

Advances in genetic testing, enable the identification of genetic causes even before symptoms appear, allowing for timely ...

For patients with localized prostate cancer (PCa), tissue-based genomic classifiers (GCs) do not consistently influence risk ...

Gene expression is the generation of a functional gene product from the information encoded by a gene, through the processes of transcription and translation. Gene products are often proteins ...

The head of Turin's Molinette Hospital Alzheimer's centre, Innocenzo Rainero, on Sunday hailed a breakthrough by Italian ...

Esophageal squamous cell carcinoma (ESCC) is a highly aggressive malignancy with poor prognosis, and understanding the ...

Jan. 28, 2025 — A 'pocket' on the protein cyclin B is responsible for ensuring that the steps of cell division take place in the correct ... First Mouse With Two Male Parents to Reach Adulthood ...

The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...

This complex process, known as gene expression, determines which proteins we make and whether we make them in the correct amounts, crucial work given that proteins play a role in virtually every a ...

Key Laboratory of Bio-chemistry Engineering - The State Ethnic Affairs Commission-Ministry of Education, Dalian Nationalities University, Dalian, China. State Key Laboratory of Fine Chemicals, Dalian ...

RFK Jr. is a high-profile face of vaccine hesitancy, but people's vaccine concerns fall on a much broader spectrum.