Initial screening assays were performed with a large number of typical and atypical antipsychotic drugs. In preliminary studies, we discovered that selected typical and atypical antipsychotic ...

This observation led Swedish investigators to propose, in 1948, that there are two types of receptors sensitive to histamine, and close to two decades later British researchers gave the name H1 to ...

For mild hives, your doctor may recommend an over-the-counter, second-generation H1 antihistamine such as fexofenadine (Allegra), loratadine (Claritin), cetirizine (Zyrtec), or desloratadine ...

In vitro tests have demonstrated that second-generation antihistamines have improved H 1-receptor specificity and a slower dissociation rate compared with first-generation antihistamines ...

It is classified as a first-generation H1 antihistamine and is primarily used for the treatment of allergies as well as motion sickness and nausea. First-generation H1 antihistamines like Benadryl ...

Histamine was identified as a pro-porphyrinogenic factor in hepatocytes. Both H1- and H2-receptor blockade were shown to decrease PP-IX levels. CCZ treatment reduced hepatic mast cell infiltration ...