With the addition of Casgevy, Children’s Hospital Los Angeles now offers two gene therapies for sickle cell, the first being Lyfgenia.

Immvention Therapeutix is partnering with Novo Nordisk to develop oral treatments for sickle cell disease (SCD) and other ...

BEAM-101 demonstrated robust and durable increases in fetal hemoglobin and reductions in ... multicenter trial in adult patients with SCD with severe vaso-occlusive crises (VOCs).

Treatment with BEAM-101 demonstrated robust and durable increases in fetal hemoglobin (HbF ... multicenter trial in adult patients with SCD with severe vaso-occlusive crises (VOCs).

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and thus mimicking the effects of naturally occurring variants seen in hereditary persistence of fetal hemoglobin. HbF is the predominant hemoglobin variant during development and early life. The ...

If you’re an adult human, odds are you already know a thing or two about tooth regeneration. Around age six, most of us begin to lose baby teeth in a process called eruption, exchanging our ...

Ghazal continued: "The regulator's long-awaited guidance on age assurance means adult content providers now have the clarity they need to get their houses in order and put in place robust and reliable ...

Fetal lung-derived alveolar type 2 (fdAT2) organoids traffic and secrete surfactant appropriately and have similar gene expression profiles to adult alveolar type 2 cells. Knock-down of the E3 ligase ...

Background: Anemia is considered a risk factor for cardiovascular disease. However, there is little evidence regarding the relationship between hemoglobin (HB) and cerebral infarction after ...