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Nature Aging:免疫系统衰退的幕后推手Sema4A缺失如何加速衰老进程?
随着年龄的增长,体内的免疫系统逐渐衰退,髓系偏向性造血干细胞的数量和功能也开始下降。研究发现,缺乏Sema4A的小鼠在衰老过程中表现出异常的髓系扩展和免疫衰退现象。具体来说,这些小鼠在衰老过程中出现了过度的中性粒细胞和血小板增多,并且其骨髓中髓系与红 ...
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