Apoptosis is dependent on caspase activation, whereas the caspase-independent necrotic signaling pathway remains largely uncharacterized. We show here that Fas kills activated primary T cells ...

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL ... TRAIL-sensitive tumor cells in vitro along with perforin and Fas ligand (FasL). Administration of neutralizing monoclonal ...

The Watermark/Faculty Success software (hereafter referred to as the “Faculty Activity System” or FAS) is the faculty activity reporting tool for the University of Oklahoma and is used to generate ...

Apoptosis is crucial for the correct development of the nervous system ... FAIM-L and SIVA-1 as Components of the Classic Apoptotic Pathway FAIM-L blocks DR-induced cell death by two main mechanisms: ...

The role of B-cell lymphoma-2 (BCL-2) ovarian killer (BOK) in apoptosis regulation has been a long-standing enigma. Despite the homology to BAX and BAK, BOK has yet to be linked to a definitive ...