Breast cancer (BC) is one of the most common malignancies and the leading cause of cancer-related mortality in women. Androgen receptor (AR) is frequently expressed in diverse BC subtypes.
SRC1 was the first cloned steroid receptor co-activator ... Figure 1: Molecular structure of SRCs and their functional mechanisms in steroid hormone-induced gene expression. In addition to serving ...
Oct. 17, 2024 — Researchers have developed strategies to identify regulators of intestinal hormone secretion. In response to incoming food, these hormones are secreted by rare hormone producing ...
This is closely related to impaired neutrophil migration in sepsis, but the mechanism involved is still unclear. Many studies have shown that chemokine receptor dysregulation is an important cause of ...
30, 2024 — Scientists have developed a molecular clock that records the ... advanced our knowledge of multiple roles for PTPRK, a receptor tyrosine phosphatase linked to the regulation of ...
This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...
Facundo’s lab studies B-cell biology and antibody responses, particularly B-cell receptor signaling dynamics, involvement of the cortical cytoskeleton ... As a postdoc, he focused on the molecular ...