The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study.
By age 75, a noteworthy 50% of men develop an inguinal (groin) hernia - a bulge that results from soft tissue pushing through a weak spot in the abdominal muscles.
The researchers found that imlunestrant prolonged progression-free survival (PFS) when compared to standard care in patients with ESR1 mutations, but there was no PFS benefit observed in the overall ...