Chlorcyclizine shows promise in reducing protoporphyrin-IX accumulation and liver damage in erythropoietic protoporphyria, ...

The disorder is marked by reticulocytopenia, which is a decrease in reticulocytes (immature red blood cells), and a notable absence of erythroid precursors in the bone marrow. Recent research has ...

Iron binds to transferrin for transport to erythroid precursor cells to be incorporated into hemoglobin. Administer as a slow continuous IV infusion over 3–4hrs via pre- or post-dialyzer ...

Higher EPO and HIF lead to the secretion of ERFE from erythroid precursor cells, which attenuates the BMP6 signaling cascade via GDF15/TWSG1. In the absence of BMP6, TMPRSS6 binds to ALK2 ...

Castruccio Castracani and his team developed a lentiviral vector that activated the human ALAS2 gene in erythroid cells, or cells that serve as precursors to normal red blood cells. They found ...