Anti-M antibodies active at 37°C are a rare cause of HDN. 1 We report data, arising from the investigation of a neonate with severe transient pure red-cell aplasia, indicating that anti-M can cause ...

Higher EPO and HIF lead to the secretion of ERFE from erythroid precursor cells, which attenuates the BMP6 signaling cascade via GDF15/TWSG1. In the absence of BMP6, TMPRSS6 binds to ALK2 ...