Under normal conditions, PKCλ/ι phosphorylates EZH2, marking it for degradation via the ubiquitin-proteasome pathway. However, in PKCλ/ι-deficient prostate cancer cells, EZH2 accumulates and shifts to ...

There are several candidates under investigation for prostate cancer for patients at various stages of the disease including an oncolytic virus, PARP inhibitor and EZH2 inhibitor. Candel ...

Key Strategies Against Drug-Resistant Prostate Cancer Nov. 20, 2024 — An enzyme called EZH2 has an unexpected role in driving aggressive tumor growth in treatment-resistant prostate cancers ...

Cancer Prevention Research publishes articles that focus on cancer prevention, preclinical, clinical, and translational research, with special attention given to molecular discoveries and an emphasis ...

Jan. 28, 2025 — A new study shows that asymptomatic brain metastasis is more common in stage 4 breast cancer patients than previously believed. The study suggests that doctors may need to ...

Myeloma, or multiple myeloma, is a cancer affecting a particular type of ... Here, authors show that inhibition of EMP1 due to EZH2 activation results in increased proliferation of myeloma cells ...

Many people become confused over the definitions of a primary vs secondary or second cancer. Primary cancer is defined as the original site (organ or tissue) where cancer began. In contrast, a second ...

Estimated numbers of new cancer cases and deaths in 2025 by cancer site and US state Current cancer incidence, mortality, and survival statistics Information on cancer symptoms, risk factors, early ...

Many people have questions about how cancer can kill you. It is something that most people worry about at some point. We know that talking about this can be difficult. So, you can save to read this ...