A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

(4) Alternatively, scientists co-opt the bacteria’s endogenous CRISPR machinery and supply only the guide RNA. (5) Scientists edit the microbe’s DNA or cause irreparable breaks that lead to DNA ...

CRISPR places an entirely new kind of power into human hands. For the first time, scientists can quickly and precisely alter, delete, and rearrange the DNA of nearly any living organism ...

The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell. After that, the next step in CRISPR gene editing is usually to alter that piece of DNA. However ...

Using this method, Samuel demonstrated that if the anti-defense genes are positioned near the DNA entry point, the plasmid successfully overcomes the CRISPR system. However, if these genes are ...

Carl Zimmer recently reported in The New York Times about a new way Crispr could be used in new ways. “The groundbreaking thing about this work is that it now opens up the RNA world to Crispr ...

Shelby is an assistant editor for The Scientist. She earned her PhD from West Virginia University in immunology and microbiology and completed an AAAS Mass Media fellowship. View Full Profile. Learn ...

As the CRISPR/Cas systems integrate DNA from invading pathogens in chronical ... bacteria that is supposed to go and share the vector/plasmid through conjugation. The conjugation process is ...

Its CRISPR/Cas9 platform is a gene editing technology that allows for precise, directed changes to genomic DNA. The firm offers a portfolio of therapeutic programs across a broad range of disease ...

It involves altering DNA to prevent disease or even to choose specific traits using a method known as CRISPR. In 2018, Chinese scientist He Jiankui created the first gene-edited babies ...