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Our work has generated investment ideas in health care, consumer electronics, finance technologies, transportation, AI-based Oppenheimer raised the firm’s price target on Ligand (LGND ...

Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, engages in the development and licensing of biopharmaceutical assets worldwide. Its commercial programs include Kyprolis and ...

P2Rank: Protein-ligand binding site prediction from protein structure based on machine learning.

What is Known About the Estrogen Deficiency of Menopause & Specific Autoimmune Diseases It is known that many natural, pathological and therapeutic conditions can change serum estrogen levels ...

MS is a multifactorial disease and vitamin D deficiency is associated with disease. Herein, we examined the impact of 1,25(OH)2D3 on CD4+ T cells coactivated by either CD28 to induce polyclonal ...

The three-signal paradigm tries to capture how the innate immune system instructs adaptive immune responses in three well-defined actions: (1) presentation of antigenic peptides in the context of MHC ...

Dual blocking SHP2 and FGFR2 can not only promote the targeted tumor-killing effects and overcome FGFR2 inhibitor resistance caused by feedback activation, but also activate T cell-mediated anti-tumor ...

Alpine’s pipeline products include povetacicept (ALPN-303) is a dual antagonist of the B cell activating factor (BAFF) and a proliferation-inducing ligand that targets systemic lupus erythematosus, ...

Hubei Key Laboratory of Electrochemical Power Sources, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, P. R. China Beijing Key Laboratory of Theory and Technology for ...