However, with age, the burden of misfolded proteins exceeds the capacity of cells to maintain proper proteome integrity, leading to disruptions in cellular function. Cumulative evidence using C.

Cell division is the process by which a parental cell gives rise to two daughter cells. The process involves both nuclear division and cytokinesis and can either produce two equal cells (symmetric ...

This study proposes that Rab conversion in both C. elegans and mammalian cells is caused by the corralling of ubiquitinated cargo by ESCRT complexes, which destabilises a Rab5 GEF (RABX-5) and leads ...

All cells are produced from other cells by the process of cell division. Cell division occurs when one cell divides to produce two new cells. Unicellular organisms use cell division to reproduce.

the presence of certain group VIIIb transition metal compounds in concentrations of about 1–10 parts per million of the metal in the culture medium causes an inhibition of the cell division ...

Mitochondria organelles came from primordial bacterial endosymbionts and still preserve distinct genes for important functions like making ATP. To speed the emerging therapeutic research into the ...

Among those downregulated were genes crucial for extracellular matrix processes and egg cell integrity. “What was very striking for us when we were looking at these genes is that they suggested that ...

For this reason, we applied CRF_ID 2.0 to aid the neuron identification in multi-cell gene expression analysis. In this work, we have upgraded and characterized the original CRF_ID method to ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

BBH1 accumulates on the day the ISMs become committed to die and is presumably liberated when Acheron is degraded. This is correlated with the release and rapid degradation of cytochrome c and the ...

The evidence they present that ASEL/R lateralization exists and is achieved by different means in P. pacificus compared to C. elegans is solid, but would be strengthened by the inclusion of calcium ...