Huntington’s disease symptoms are linked to expanding DNA repeats (CAG) that become toxic in brain cells over time The "ticking DNA clock" accelerates after 80 repeats, killing neurons within ...

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The Huntington disease mutation forms the core, but it is the fuzzy coat on the surface that is exposed to the brain cell environment. This fuzzy coat can then engage with cellular components and ...

The most well-known person with Huntington's Disease was singer-songwriter Woody Guthrie, author of "This Land is Your Land," who died in 1967 at age 55. Although treatment of symptoms has ...

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Copyright 2025 The Associated Press. All Rights Reserved. This microscope photo provided by the McLean Hospital’s Harvard Brain Tissue Resource Center in January ...

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This type of "somatic expansion" occurs in only the specific types of brain cells that later die in Huntington's disease. Only once a cell's DNA expansion reaches a threshold number of CAGs ...