MYC is a pleiotropic transcription factor involved in multiple cellular processes. While its mechanism of action and targets are not completely elucidated, it has a fundamental role in cellular ...

No writing assistance was utilized in the production of this manuscript. Monoclonal antibodies are novel therapeutic agents used with great success in the treatment of rheumatoid arthritis (RA).

After incubation with corresponding secondary antibodies for 2hrs at room temperature ... we demonstrated that RHPN2 upregulated the expression of glutamine synthetase through stabilizing the ...

M. Conacci-Sorrell et al., “Myc-nick: a cytoplasmic cleavage product of Myc that promotes α-tubulin acetylation and cell differentiation,” Cell, 142:480-93, 2010. Free F1000 Evaluation When Maralice ...

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After 48 hours the live cells were incubated for 2 hours with a c-myc (DyLight 550) monoclonal antibody (Myc.A7, ThermoFisher Scientific) to label GLDN at the cell surface. Cells were washed 3 times ...

Different types of antibodies are produced by your immune system. These five antibodies help fight disease by detecting viruses, bacteria, and other pathogens (disease-causing microorganisms) and ...

A thyroglobulin antibody (TgAb) test looks for certain antibodies that attack the thyroid. The presence of TbAb in high levels may indicate that someone has an autoimmune condition. To conduct a ...

either alone or in combination with the pan-mTOR inhibitor MLN0128 or the checkpoint inhibitor anti-PD-L1 antibody. Results Cabozantinib treatment led to stable disease in c-Met/β-catenin and ...

Figure 1: Transgene expression and phenotype. Figure 2: K14.MYC2 mice exhibit impairment in wound healing. Figure 3: K14.MYC2 primary keratinocytes exhibit a defect in migration. Figure 4: K14 ...

Sjögren’s antibody testing is done using a blood sample. It checks antibody levels, including anti-SS-A (also called anti-Ro) and anti-SS-B (also called anti-La). Anti-SS-A and anti-SS-B are ...