The grand challenge in structure-based drug design is achieving accurate prediction of binding free energies. Molecular dynamics (MD) simulations enable modeling of conformational changes critical to ...

A team led by UT Southwestern Medical Center researchers has identified a key mechanism responsible for endosomal recycling ...

Here we review the biology of Pf phage and what is known about its contributions to pathogenesis and clinical disease. First, we review the structure, genetics, and epidemiology of Pf phage. Next, we ...

The All-Star circuit has come and gone and two new challenges await draftniks everyone. First and foremost, not overreacting ...

Researchers at UT Southwestern identified how SNX17 and Retriever interact to regulate endosomal recycling, a crucial process ...

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