The essential physiologic function of ACTH is to stimulate cortisol production. It has other important actions in stimulating both mineralocorticoid production from the zona glomerulosa and ...

Corticosteroid signaling by glucocorticoids is mediated through two distinct intracellular receptor subtypes referred as the mineralocorticoid ... on cortisol and ACTH responses to psychosocial ...

Abbreviations: ACTH = adrenocorticotropic hormone; AME = apparent mineralocorticoid excess; CAH = congenital adrenal hyperplasia; DOC = deoxycorticosterone; FH-I = familial hyperaldosteronism type ...