A study led by Turkish researcher Pinar Ayata unveiled a critical mechanism involving microglia—specialized immune cells in the brain—that could open new avenues for treating Alzheimer's ...
A preliminary experiment was conducted to determine the response of microglia to varying doses of LPS. Microglia were exposed to 1 ng/ml, 10 ng/ml and 100 ng/ml of TNFα for 24 hours. This ...
During development, there are known sex-related differences in how microglia function. But into adulthood, there was thought to be less variation in how they behave. Microglia maintain neuronal ...
Whether the mitochondrial respiratory chain is necessary for the function and proliferation of microglia, however, has remained unknown. Previous work from Chandel's laboratory, published in ...