Alternatively, an inhibitor might suffer a loss-of-function mutation, lose its ability to regulate signalling and lose its functions as a tumour suppressor. Both types of change in Wnt signalling ...

该研究结果表明，KAT6A- RSPO2- Wnt信号在调节海马CA3突触可塑性和认知功能中起着关键作用，为KAT6A综合征及相关神经发育疾病提供了潜在的治疗靶点。

Matthew Caufield, an analyst from H.C. Wainwright, has initiated a new Buy rating on Surrozen (SRZN).Invest with Confidence: Follow TipRanks' ...

Dewpoint Therapeutics’ second development candidate, DPTX3496 is an oral, small molecule acting via a novel ...

Allarity Therapeutics, Inc. (“Allarity” or the “Company”) (NASDAQ: ALLR), a Phase 2 clinical-stage pharmaceutical company ...

Scientists have uncovered a key mechanism in jellyfish embryos that provides new insights into how the body plan of these ...

nucleatum) can pose risks for colorectal cancer by activating the Wnt/β-catenin pathway. Nevertheless ... and eliminate tumor ...

A study that evaluated how biochemical inhibition of endogenous Wnt signaling affects barrier functions of the junctional epithelium was presented at the 102nd General Session of the IADR ...

By directly targeting the β-catenin TCF4 protein-protein interaction, FOG-001 is intended to block the Wnt signaling pathway irrespective of the various APC and beta-catenin mutations that ...