Figure 5: The chromatin-associated small interfering RNA (siRNA) pathway in Arabidopsis ... Dicer proteins and processing cofactors, as well as RdRPs in some lineages, have specialized to produce ...

Single-stranded RNA molecule (usually from 21 to 25 nucleotides in length) produced by the cleavage and processing of double-stranded RNA; binds to complementary sequences in mRNA and brings about ...

In SNALPs, the backbone-modified siRNA is encapsulated within a closed shell of a cationic-zwitterionic lipid bilayer, furnished with an outer PEG shield (Figure 2A). The lipid bilayer contains a ...