By creating gene editors not found in nature, or optimizing existing editors, AI can improve the accuracy, effectiveness, and accessibility of gene editing.
This illustration compares various gene editing technologies, including meganucleases, zinc finger nucleases, TALENs, and CRISPR/Cas9, along with their relative feasibility and mechanisms of DNA ...
"We believe Sangamo's zinc finger nucleases provide the optimal gene-editing platform, and we look forward to working with Sangamo to accelerate our efforts to develop next-generation autologous ...
However, it is difficult to determine in advance exactly where the gene will be inserted, as the recognition sequences of most restriction ... Another result of this research are zinc finger nucleases ...
Both gene knockout and knock-in models are powerful ... associated with superior efficacy in knocking down genes 1.