In a nutshell Female cells randomly use either the maternal or paternal X chromosome—this study shows that relying more ...

New research is offering deeper insights into the role of the active X chromosome and its effects on brain health.

A UCSF study reveals that maternal X chromosome expression may accelerate brain aging and cognitive decline. Female mice with ...

Carrying out detailed analyses of the brain cells, the team was then able to identify certain genes that were completely silenced on maternal X chromosomes but not paternal ones. When the researchers ...

The X and Y chromosomes, commonly referred to as the sex chromosomes, are one such pair. They determine the biological sex, reproductive organs, and sexual characteristics that develop in a person.

When the researchers used CRISPR gene editing technology to activate the silenced genes on maternal X chromosomes in female mice, they became smarter in their old age. "Together, all these ...

A new study reveals that the maternal X chromosome may accelerate brain ageing and increase Alzheimer's risk. Experiments on female lab mice showed that older mice with only the maternal X ...

Researchers aim to continue studying the role of the X chromosome in brain aging, and whether it can explain people’s risk of ...

Males, with their single X chromosome, arise due to errors during X chromosome segregation and make ... This stalled meiotic progression coincided with the activation of a DNA damage checkpoint, ...