Physiological extracellular matrix (ECM) calcification or mineralization is restricted to bones, teeth and the hypertrophic zone of growth plate cartilage. In contrast, pathological ECM ...

Cartilage calcification is associated with knee osteoarthritis (OA). A study by Mitsuyama et al., however, suggests that calcification is primarily a consequence of aging rather than OA.

Real-time observation of certain biochemical processes in blood vessels from mice has revealed a previously unknown similarity between atherosclerosis, also known as vascular calcification ...